PE-conjugated Anti-TNFSF15 antibody(DMC464); IgG1 Chimeric mAb

Price: 100 test $550.00

SKU: DMC100464P Category: Monoclonal antibodies

Clone ID	DMC464
Target	TNFSF15
Synonyms	TL1; VEGI
Host Species	Rabbit
Description	PE-conjugated Anti-TNFSF15 antibody(DMC464); IgG1 Chimeric mAb
Delivery	3-4 weeks
Uniprot ID	O95150
IgG type	Rabbit/Human Fc chimeric IgG1
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Liquid，PBS with 0.05% Proclin300, 1% BSA
Storage & Shipping	Store at 2°C-8°C for 6 months
Background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells; but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21:DR6. It can activate NF-kappaB and MAP kinases; and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation; and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Feb 2011]
Usage	Research use only
Conjugate	PE-conjugated