Clone ID | DMC440 |
---|---|
Target | |
Synonyms | ATF; BDPLT5; QPD; u-PA; UPA; URK |
Host Species | Rabbit |
Description | PE-conjugated Anti-UPA antibody(DMC440); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | P00749 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-UPA antibody(DMC440); IgG1 Chimeric mAb
Price: 100 test $550.00
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