Human 5HT1E-Strep full length protein-synthetic nanodisc

Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00

SKU: FLP120164 Category: Full Length Transmembrane Proteins

Tag	C-Flag&Strep Tag
Target	5HT1E
Synonyms	5-HT1E
Description	Human 5HT1E-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P28566
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,Monoamine GPCRs,
Molecular Weight	The human full length 5HT1E-Strep protein has a MW of 41.7 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated