| Tag | C-Flag&Strep Tag |
|---|---|
| Target | |
| Synonyms | GALNR, GALNR1 |
| Description | Human GALR1-Strep full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | P47211 |
| Expression Host | HEK293 |
| Protein Families | Transmembrane,Druggable Genome, |
| Protein Pathways | GPCRDB Class A Rhodopsin-like,Peptide GPCRs,Metabolic and Obesity, |
| Molecular Weight | The human full length GALR1-Strep protein has a MW of 39 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human GALR1-Strep full length protein-synthetic nanodisc
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00
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