Name: Human GBRA3-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120802

Tag	C-Flag&Strep Tag
Target	GBRA3
Synonyms	N/A
Description	Human GBRA3-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P34903
Expression Host	HEK293
Protein Families	Ion Channels: Cys-loop Receptors
Protein Pathways	N/A
Molecular Weight	The human full length GBRA3-Strep protein has a MW of 55.2 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human GBRA3-Strep full length protein-synthetic nanodisc