Name: Human GPR85-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120320

Tag	C-Flag&Strep Tag
Target	GPR85
Synonyms	SREB, SREB2
Description	Human GPR85-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P60893
Expression Host	HEK293
Protein Families	GPCR,Transmembrane,Druggable Genome,
Protein Pathways	GPCRDB Class A Rhodopsin-like,
Molecular Weight	The human full length GPR85-Strep protein has a MW of 42 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
Usage	Research use only
Conjugate	Unconjugated

Human GPR85-Strep full length protein-synthetic nanodisc