Name: Human HCN2-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120752

Tag	C-Flag&Strep Tag
Target	HCN2
Synonyms	BCNG-2, BCNG2, HAC-1
Description	Human HCN2-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q9UL51
Expression Host	HEK293
Protein Families	Ion Channels: Cyclic nucleotide gated
Protein Pathways	N/A
Molecular Weight	The human full length HCN2-Strep protein has a MW of 97 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
Usage	Research use only
Conjugate	Unconjugated

Human HCN2-Strep full length protein-synthetic nanodisc